Guest student at IHRS, BioSoft in Germany

Guest student at IHRS, BioSoft in Germany

Bacteria adapt to the external stress through forming community called bacterial biofilms to increase their survival rate. I studied the structure of a wild type, and genetically modified bacterial biofilms, so we can tune the forces exerted by the pili motors, of Neisseria gonorrhoeae, responsible for sexually transmitted infection gonorrhea; as well as the effect of different anti-biotics at Dr. Berenike Maier’s lab. I used confocal laser scanning microscope to get 3D image stack of the fixed biofilm then I tracked the cells in it using MATLAB. From the coordinates of the cells, we can compute the radial distribution function of each biofilm which shows the structure or range of interaction of the biofilm. Follow here about the program. (July – October 2017)